| Recombinant Human Protocadherin α-6/PCDHA6 | |
| Catalog# | C817 |
| Source | HEK293 |
| Description | Recombinant Human Protocadherin α-6/PCDHA6 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln30-Asn697) of Human PCDHA6 fused with a 6His tag at the C-terminus. |
| Names | Protocadherin Alpha-6, PCDH-Alpha-6, PCDHA6, CNRS2 |
| Accession # | Q9UN73 |
| Shipping | The product is shipped on dry ice/ice packs. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Endotoxin | Less than 0.1 ng/μg (1 IEU/μg). |
| Amino Acid Sequence | QLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDLLEVNLQNGILFVNSRIDREE LCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASD ADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTG TVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMV IDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTS LSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVS AYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA QENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKAS SRASVGAAGPEAALVDVNVDHHHHHH |
| Background | Protocadherin α-6 (PCDHA6) is a single-pass type I membrane protein that contains six cadherin domains. PCDHA6 is a member of the protocadherin α gene cluster. The α gene cluster is composed of 15 cadherin superfamily genes related to CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA6 is a potential calcium-dependent cell-adhesion protein. PCDHA6 may be involved in the establishment and maintenance of specific neuronal connections in the brain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. |
| MSDS |  |